This paper presents an introduction to the Multimodal Interaction in Psychopathology workshop, which is held virtually in conjunction with the 22nd ACM International Conference on Multimodal Interaction on October 25th, 2020. This workshop has attracted submissions in the context of investigating multimodal interaction to reveal mechanisms and assess, monitor, and treat psychopathology. Keynote speakers from diverse disciplines present an overview of the field from different vantages and comment on future directions. Here we summarize the goals and the content of the workshop.